Endocrine Abstracts

The effectiveness of thyroid remnants ablation with 131I after thyroidectomy for differentiated thyroid carcinoma (DTC) depends mainly on absorbed radiation dose, which is proportional to 131I uptake (Tup) and its effective half-life time (EHL) in the remnants.Aim: Assessment of endogenous TSH level increment effects on EHL of 131I and Tup in thyroid remnants after surgery for DTC.Material: Twenty-o...

Sclerostin, a product of a SOST gene, is a protein expressed by osteocytes that inhibits osteoblastic bone formation. Several hormones including PTH and glucocorticosteroids and have been suggested as possible regulators of sclerostin production. The influence of thyroid hormones on sclerostin synthesis has not been investigated so far. The aim of the study was to evaluate sclerostin concentrations in patients before and after treatment of thyrotoxicosis.<p class="abstext"...

Goiter prevalence (GP) and median UIC in population studies are both considered markers of iodine nutrition. Controversy exists which of them is more reliable.Aim: To assess correlation between UIC and thyroid volume in Polish schoolchildren.Material and methods: 9402 Polish schoolchildren (51.3% girls, 48.7% boys) aged 6–12 years were examined in 1999–2011 (‘Thyromobil’ action). 40.9% of children were born at l...

Introduction: Characteristic localisations of metastases of differentiated thyroid carcinoma (DTC) include local lymph nodes, the lungs and bones, while the incidence of DTC metastases onto the liver, the brain and skin is clearly lower. The localisation of metastases in other organs, including the kidneys, is very rare.Material and methods: A case of a 73–year-old patient with thyroid oxyphilic carcinoma is reported, the case being diagnosed in 199...

Introduction: An increase of thyroid iodine uptake (Tup) is one of the symptoms of thyrocyte stimulation by means of recombinant human thyrotropin (rhTSH). Low Tup, characteristic of iodine induced hyperthyroidism, creates serious problems, when 131I is considered, making this kind of treatment difficult, if not impossible.Material and methods: We report a case of a 74 years old patient, with hyperthyroidism, induced by amiodarone administrati...